The Holosun Laser & Weaponlights is a class IIIa visible red laser aiming device with a coaxial mounted class 2 IR (infrared) laser for use with night vision devices. The LS221R features a 7075-aluminum matte black anodized housing with a quick release Picatinny rail mount. The LS221R is powered by a single CR123 battery which can provide up to 5000 hours of battery life.

The rear facing selector switch lets the user select between visible low, visible high, IR low, IR high activation using the included remote pressure switch or turn the unit OFF. The LS221R also includes tactile windage and elevation adjustments for a precision zero.